INTRODUCTION

Adhesive dentistry has seen significant advancements over the past decades. Initially, dental adhesives evolved from no-etch systems to etch-and-rinse systems, which consisted of multiple components. From then on, manufacturers shifted focus toward simplifying the procedure. Different generations of self-etch adhesives and, finally multi-mode or universal adhesives were the result. The latter category, introduced in the early 2010s, nowadays comprises numerous products offered by many different manufacturers.

In general, universal adhesives offer more procedural freedom and simplicity than multi-step, multi-bottle systems as well as good adhesion. According to a recent review¹, adhesive properties have improved and manufacturers have also succeeded in reducing the technique sensitivity of the adhesive systems. However, hybrid layer degradation still seems to be a relevant issue for many modern products available on the market. Moreover, feedback from clinicians reveals that there are several areas of concern where bonding systems in general can be improved. These include the risk of contamination due to a lengthy procedure or the need for rubbing, pooling of the adhesive in corners and accumulation along margins. Moreover, some adhesives are challenging to introduce into narrow cavities, while their curability may be limited.

That is why Kuraray Noritake Dental Inc. decided to develop a new-generation universal adhesive that addresses these areas of concern: CLEARFIL™ Universal Bond Quick 2. This latest evolution in dental bonding technology is based on decades of knowledge in the development of clinically successful dental adhesives at Kuraray Noritake Dental Inc. It retains all the benefits of its predecessor – the current extensively tested and clinically proven CLEARFIL™ Universal Bond Quick – adding higher strength and improved handling.^2-5

THE ESSENTIAL BENEFITS OF CLEARFIL Universal Bond Quick 2

CLEARFIL Universal Bond Quick 2 offers the following essential benefits:

• Quick and straightforward application procedure
• High-strength bonding layer
• Consistently durable bond
• Ease of application
• Minimised risk of pooling
• Procedural freedom
• Immediate availability for clinical use

For all those who wonder how the improvements were implemented, which technologies are responsible for them and whether there is scientific proof, the following paragraphs are worth reading. They summarize essential general knowledge about adhesive formulations, explain potential issues and their causes, and address every benefit featured by CLEARFIL Universal Bond Quick 2, explaining all the important details around it.

KEY COMPONENTS OF UNIVERSAL ADHESIVES

Universal adhesives are based on highly complex formulations with many different constituents and technologies combined in a single bottle. The most essential parts found in virtually every universal adhesive are:

RESIN COMPONENTS

Just like composite restorative materials, dental adhesives are resin-based materials. This means that different kinds of cross-linking and functional monomers are the beating heart of the formulation. Functional monomers are initially hydrophilic and form linear polymers upon curing, while cross linking polymers are hydrophobic and form stronger, highly cross-linked polymer networks.⁶ They are added to adhesive formulations to fulfil different tasks: some monomers are used to promote adhesion to tooth structure or composite resin, while others are used as etching or demineralizing agents, wetting enablers, and agents promoting penetration into the tooth structure. Hence, they have an impact on application properties, bond strength to various substrates including enamel and dentin, strength, hydrolytic stability and overall durability of the bonding layer, and more.

INITIATORS

To provide for a high strength of the adhesive layer and a favourable degree of conversion, dental adhesives are typically cured before the composite is applied. Universal adhesives contain a photo initiator that sets off the radical polymerisation reaction when light of a specific wavelength is absorbed. Chemical initiators are found in self- or dual-cure resin cements, but not in single-bottle adhesives. Studies have revealed that the initiator concentration has an impact on the mechanical properties of the materials they are part of ^6,7.

FILLERS

Unlike composite restorative materials, which are always filled, dental adhesives may or may not contain fillers. Fillers are usually added for two main reasons: to increase the viscosity of the adhesive and to strengthen the adhesive layer. The viscosity has a direct impact on the thickness and quality of the adhesive layer. If the viscosity is too low, the risk increased of some areas of the tooth structure remaining uncovered resulting in an incomplete adhesive layer. In addition, an overly thin adhesive layer may be weak due to the inhibition of oxygen, which prevents proper curing of the contained resin⁶. If the viscosity is too high, however, application into the root canal and deep Class II cavities is often difficult thus increasing the risk of pooling or adhesive accumulation along margins. Moreover, air-blowing and complete solvent evaporation may also prove challenging.

SILANE COUPLING AGENT

A silane coupling agent is usually part of the formulation as well. They are the link between the resin matrix and the filler particles in the formulation and offer protection against degradation.

SOLVENTS

Solvents – typically water and ethanol or acetone – are essential parts of adhesive formulations. This is because dentin only bonds well to hydrophilic materials. Together with the hydrophilic monomers found in the formulation, the solvents provide for an environment favourable for dentin bonding⁶. Moreover, their task is to re-expand the collapsed collagen fibrils on the demineralized dentin surface. Most modern dental adhesives contain water and ethanol as solvents. However, ethanol cannot be used in combination with certain types of monomers.

CHEMISTRY IMPROVEMENTS ENABLING THE ESSENTIAL BENEFITS

There are certain components and technologies, like monomers and monomer combinations, which are used by various dental industry manufacturers in their universal adhesives. While some certainly offer advantages, potential drawbacks lie in their toxicity in the uncured state, possible unwanted interactions with other components and the like.

Many of the essential benefits of CLEARFIL Universal Bond Quick 2 are due to improvements or changes in those key components. Specifically, the resin formulation and the filler technology have been altered to provide for higher strength and an improved handling. The following paragraphs will describe the changes, the key components used and the benefits arising from them.

1. RESIN TECHNOLOGY: QUICK AND STRAIGHTFORWARD APPLICATION PROCEDURE

Adhesive penetration into the tooth structure is strongly influenced by monomers contained in the formulation. A monomer commonly used for this purpose is the highly hydrophilic hydroxyethylmethacrylate (HEMA)⁶. Although HEMA provides important benefits such as supporting homogeneous integration of components within the adhesive, its hydrophilic character – even after polymerization – may lead to water sorption, which can negatively influence the long-term mechanical properties of adhesive systems⁸. According to the results of an in-vitro study, high concentrations of HEMA in adhesive formulations may not only lead to poor mechanical properties (including bond strength), but also to a higher risk of bond degradation⁹. For these reasons, reducing the dependency on high levels of HEMA in universal adhesives and complementing it with alternative monomers is considered advantageous. However, this measure requires careful selection of the alternative monomer and precise alignment with the existing ingredients to prevent negative effects. In some cases, manufacturers have selected alternative monomers that lead to a lower bond strength or (unlike HEMA) lead to cytotoxic effects even after polymerisation¹⁰.

In CLEARFIL Universal Bond Quick and the brand-new universal adhesive CLEARFIL Universal Bond Quick 2, Kuraray Noritake Dental Inc. have incorporated an amide monomer that significantly decreases the need for HEMA. In in-vitro tests, this monomer did not show any cytotoxic effects¹⁰, while it is responsible for one of the essential benefits – the extremely quick and straightforward application procedure. It gives the adhesive its hydrophilicity in the initial, uncured state. During polymerisation, a stable, hydrophobic cross-linked network is formed. The network contributes to the durability of the bond, also thanks to its water-resistant property.

CLEARFIL Universal Bond Quick 2 takes just seconds to apply as there is no need to wait for the adhesive to penetrate the tooth structure. This feature was originally developed for its predecessor CLEARFIL Universal Bond Quick and was carried over as it turned out to work well¹¹ and has been very well received by clinicians from all over the world. Eliminating the need to wait after application speeds up the procedure, saves time and minimises the risk of contamination. This is particularly useful in situations where moisture control is a challenge or where a patient is impatient – e.g. in paediatric dentistry.

2. RESIN TECHNOLOGY: HIGH-STRENGTH BONDING LAYER

The stronger the bonding layer, the higher its resistance to shrinkage forces. Hence, it seems worth striving for a strong bonding layer to enhance the longevity of both bond and restoration. A popular strategy is the adding of cross-linking bi-or multi-functional monomers to the formulation^6,12. While the most frequently used monomers added for this purpose are UDMA, Bis-GMA and TEGDMA, Kuraray Noritake Dental Inc. added the Urethane Tetra Methacrylate Monomer (UTMA) to add mechanical strength to the adhesive system.

UTMA is a functional monomer that, due to its multiple curable sites, provides for an increased strength of the bonding layer. Both nano-hardness and ultimate tensile strength are extraordinarily high. Consequently, the adhesive offers the desired increased resistance to shrinkage forces. Moreover, it forms a highly curable, thin bonding layer.

3. RESIN TECHNOLOGY: CONSISTENTLY DURABLE BOND

The third monomer forming the advanced rapid layer technology found in CLEARFIL Universal Bond Quick 2 is the proven functional acidic monomer invented by Kuraray Noritake Dental Inc.: the Original MDP Monomer. MDP is not only well-known for its high affinity to hydroxyapatite, but also several other materials, including metals and zirconium oxide. In various studies, it has been proven to deliver an outstanding bonding performance over time^13,14.

This applies specifically to the original MDP monomer produced by Kuraray Noritake Dental Inc. In a study, it was shown that the quality and performance of the functional monomer may be different depending on how it is produced: MDP from other manufacturers contained impurities and dimer, which had a negative effect on the bonding performance of the respective adhesives¹⁵. Only the original MDP monomer exhibited a high purity and contained no dimer, with better bonding outcomes.

WATCH THE VIDEO ABOUT ADVANCED RAPID BOND TECHNOLOGY

4. FILLER TECHNOLOGY: EASE OF APPLICATION

The flow properties of an adhesive are a critical factor: as mentioned earlier, achieving an optimally formed and uniformly distributed adhesive film is essential for reliable clinical performance. Moreover, the right flow properties improve the application procedure. To realize improved flow properties without altering the filler content (which might negatively influence the mechanical strength), Kuraray Noritake Dental Inc. has redesigned the filler dispersion method originally employed by the company. The new way of adding fillers and different monomers to the formulation leads to low filler agglomeration.

Consequently, CLEARFIL Universal Bond Quick 2 is very easy to apply. Its low viscosity allows the adhesive to flow effortlessly even into narrow or hard-to-reach areas, supporting precise placement and uniform coverage.

Finally, air-blowing is easier to perform on a thin layer than when the layer is highly viscous and thick: The adhesive is evenly distributed and thinned out with a gentle stream of air. If performed correctly, this measure has a positive impact on bond stability and longevity according to scientific studies^8,16. Despite an increased flowability, the filler content in CLEARFIL Universal Bond Quick 2 is similar to that of its predecessor CLEARFIL Universal Bond Quick in supporting the formation of a strong bond.

The low viscosity of CLEARFIL Universal Bond Quick 2 allows the adhesive to flow effortlessly even into narrow or hard-to-reach areas, supporting precise placement and uniform coverage.

5. FILLER TECHNOLOGY: MINIMISED RISK OF POOLING

The new filler dispersion method also enables the formation of a thin, uniform layer independent of the cavity shape. The formation of an undesirably thick bonding layer along the margins and adhesive pooling at the bottom of the cavity are clearly a thing of the past. This is particularly advantageous in the context of creating restorations in the aesthetic zone or cementation procedures employing Immediate Dentine Sealing (IDS).

6. PROCEDURAL FREEDOM

CLEARFIL Universal Bond Quick 2 is universally applicable: It can be used in self-etch, selective etch and total-etch techniques and is thus suitable for many clinical situations and for all types of users independent of their personal preferences.

Moreover, it is approved for an extremely wide range of indications. Procedures are simplified as fewer bottles and fewer steps are required: The need for etching is eliminated, as is the need for a separate dual-cure activator when the product is used with other manufacturers’ self-adhesive cements.

CLEARFIL Universal Bond Quick 2 forms the connection between several universal resin-based products of Kuraray Noritake Dental Inc.’s portfolio:

• CLEARFIL MAJESTY™ ES-2 Universal
• CLEARFIL MAJESTY™ ES Flow Universal
• PANAVIA™ SA Cement Universal

7. IMMEDIATE AVAILABILITY FOR CLINICAL USE

Due to the carefully selected components and their precise alignment, the chemistry found in CLEARFIL Universal Bond Quick 2 is highly stable. Filler particles are extremely unlikely to agglomerate, and the novel formulation allows for storage at room temperature. This is a big advantage, as it provides for the fact that the product is always ready for use and readily available. The formulation of CLEARFIL Universal Bond Quick 2 is optimised so that it may be stored at temperatures between 2 and 25° C (36-77°F).

CLINICAL WORKFLOWS

Explore the clinical videos demonstrating how CLEARFIL Universal Bond Quick 2 can be seamlessly integrated into different workflows.

DIRECT RESTORATION WORKFLOW

CLEARFIL Universal Bond Quick 2 + CLEARFIL MAJESTY™ ES-2 Universal

DIRECT RESTORATION WORKFLOW

CLEARFIL Universal Bond Quick 2 + CLEARFIL MAJESTY™ ES Flow Universal (Super Low)

DIRECT RESTORATION WORKFLOW

CLEARFIL Universal Bond Quick 2 + CLEARFIL MAJESTY™ ES Flow Universal (Low)

POST CEMENTATION & CORE BUILD-UP WORKFLOW

CLEARFIL Universal Bond Quick 2 + CLEARFIL™ DC CORE PLUS

HOW TO CEMENT INDIRECT RESTORATIONS

CLEARFIL Universal Bond Quick 2 + PANAVIA™ SA Cement Universal

HOW TO SEAL A PREPARED ABUTMENT TOOTH

CLEARFIL Universal Bond Quick 2

CONCLUSION

Kuraray Noritake Dental Inc. is committed to continuous improvement in dentistry. With the ultimate goal of making dental professionals’ lives easier and patients happier, the company combines research, development and innovation with Japanese perfection to introduce products that make all the difference.

Decades of experience and access to highly developed adhesive technologies enable the team of researchers to develop new adhesive formulations with well-balanced properties like CLEARFIL Universal Bond Quick 2. The product handles well, is based on proven components and adds decisive innovative technologies to provide for an even better bonding performance and straightforward application.

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References

1. Breschi L, Maravic T, Mazzitelli C, Josic U, Mancuso E, Cadenaro M, Pfeifer CS, Mazzoni A. The evolution of adhesive dentistry: From etch-and-rinse to universal bonding systems. Dent Mater. 2025 Feb;41(2):141-158.
2. Jaggi M, Karlin S, Zitzmann NU, Rohr N. Shear bond strength of universal adhesives to human enamel and dentin. J Esthet Restor Dent. 2024 May;36(5):804-812.
3. Peumans M, Vandormael S, De Coster I, De Munck J, Van Meerbeek B. Three-year Clinical Performance of a Universal Adhesive in Non Carious Cervical Lesions. J Adhes Dent. 2023 Jun 8;25(1):133-146. doi: 10.3290/j.jad.b4186751. PMID: 37387551.
4. de Almeida RAM, Lima SNL, Nassif MV, Mattos NHR, de Matos TP, de Jesus Tavarez RR, Cardenas AFM, Bandeca MC, Loguercio AD. Eighteen-month clinical evaluation of a new universal adhesive applied in the “no-waiting” technique: a randomized clinical trial. Clin Oral Investig. 2023 Jan;27(1):151-163. doi: 10.1007/s00784-022-04703-7. Epub 2022 Sep 6. PMID: 36068369; PMCID: PMC9447982.
5. De Almeida R, Siqueira F, Verde T, Naupari-Villasante R, Reis A, Loguercio AD, Cardenas A. Prolonged application time effects on universal adhesives in non-carious cervical lesions: An 18-month split mouth randomized clinical trial. J Dent. 2024 Jan;140:104800. doi: 10.1016/j.jdent.2023.104800. Epub 2023 Dec 4. PMID: 38056759.
6. Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, Coutinho E, Suzuki K, Lambrechts P, Van Meerbeek B. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials 2007; 28(26):3757-85.
7. Kalliyana Krishnan V, Yamuna V. Effect of initiator concentration, exposure time and particle size of the filler upon the mechanical properties of a light-curing radiopaque dental composite. J Oral Rehabil. 1998 Oct;25(10):747-51.
8. Hosaka K, Nakajima M, Takahashi M, Itoh S, Ikeda M, Tagami J, Pashley DH. Relationship between mechanical properties of one-step self etch adhesives and water sorption. Dent Mater. 2010 Apr;26(4):360-7.
9. Collares FM, Ogliari FA, Zanchi CH, Petzhold CL, Piva E, Samuel SM. Influence of 2-hydroxyethyl methacrylate concentration on polymer network of adhesive resin. J Adhes Dent. 2011 Apr;13(2):125-9. doi: 10.3290/j.jad.a18781. PMID: 21594225.
10. Wawrzynkiewicz A, Rozpedek-Kaminska W, Galita G, Lukomska-Szymanska M, Lapinska B, Sokolowski J, Majsterek I. The Toxicity of Universal Dental Adhesives: An In Vitro Study. Polymers (Basel). 2021 Aug 10;13(16):2653.
11. Ahmed MH, Yoshihara K, Mercelis B, Van Landuyt K, Peumans M, Van Meerbeek B. Quick bonding using a universal adhesive. Clin Oral Investig. 2020 Aug;24(8):2837-2851.
12. Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G. Classification review of dental adhesive systems: from the IV generation to the universal type. Ann Stomatol (Roma). 2017 Jul 3;8(1):1-17.
13. Fehrenbach J, Isolan CP, Munchow EA. Is the presence of 10-MDP associated to higher bonding performance for self-etching adhesive systems? A meta-analysis of in vitro studies. Dent Mater. 2021 Oct;37(10):1463-1485.
14. Carrilho E, Cardoso M, Marques Ferreira M, Marto CM, Paula A, Coelho AS. 10-MDP Based Dental Adhesives: Adhesive Interface Characterization and Adhesive Stability-A Systematic Review. Materials (Basel). 2019 Mar 7;12(5):790.
15. Yoshihara K, Nagaoka N, Okihara T, Kuroboshi M, Hayakawa S, Maruo Y, Nishigawa G, De Munck J, Yoshida Y, Van Meerbeek B. Functional monomer impurity affects adhesive performance. Dent Mater. 2015 Dec;31(12):1493-501.
16. Abu-Nawareg MM, Nassar HM, Sonbul HM. Enhancing bond stability: impact of adhesive thinning on resin-dentin bonded interfaces. Eur Rev Med Pharmacol Sci. 2023 Oct;27(20):9628-9638.

USER FEEDBACK ON PROCEDURES AND OUTCOMES

The use of universal products – whether solitary or combined – offers practical benefits, which are experienced differently depending on the clinical context, techniques selected and each user’s individual preferences. Key advantages include reduced treatment time, lower costs, fewer components and steps, fewer potential errors and ultimately more satisfied patients. The following compilation of statements from experienced dental practitioners on the universal concept and the products offered by Kuraray Noritake Dental Inc. in general will help you assess in what way they might allow you to elevate your workflows.

RATIONALIZING CLINICAL WORKFLOWS

Streamlining or rationalizing clinical workflows in restorative dentistry is always worth striving for. Procedures are often complex and materials demand strict adherence to recommended protocols, so that using universal solutions with standardized protocols for a wide range of indications is a promising approach. Dr José Ignacio Zorzin, Associate Professor at the Department of Operative Dentistry and Periodontology at the Friedrich-Alexander-University of Erlangen-Nürnberg in Erlangen, Germany, stated in an article: “Rationalizing clinical workflows: This is the main reason for the use of universal products in adhesive dentistry. They are suitable for a wide range of indications and different application techniques, fulfil their tasks with fewer components than conventional systems and often involve fewer steps in the clinical procedure.”

INCREASING PREDICTABILITY AND EFFICIENCY

Predictability and efficiency in direct posterior restoration procedures are the main reasons for Dr Koray Kendir, the co-founder of a private dental clinic in İzmir, Turkey to choose universal adhesives and composites. In a case report, he stated that “the combination of CLEARFIL™ Universal Bond Quick 2 and CLEARFIL MAJESTY™ ES Flow Universal allows clinicians to perform predictable, efficient posterior restorations. Their universal applicability and handling properties align with the “Universal Excellence” concept, supporting simplified, yet reliable daily practice.”

Fig. 1. Clinical image from the case report of Dr Koray Kendir: Cavities ready for the restorative procedure.

Fig. 2. Clinical image from the case report of Dr Koray Kendir: Occlusal view of the teeth restored with a universalshade flowable composite with super-low flowability.

GETTING A GRIP ON COSTS

Dr Alessandro Devigus, the owner of a private practice in Bülach, Switzerland, shared in an interview that the cost factor is most important for him: “In the first place, using fewer products and components that are easy and quick in their application allows me to get a grip on costs. With fewer steps and fewer bottles, shortened application times and standardized workflows, the time a patient needs to sit in the chair is reduced, which allows me to save the most valuable factor in the office: my time.” And there is even more to it: “At the same time, material storage and order management are streamlined, so that it is much easier to keep track of dates of expiry, hence saving material costs as well. And the best thing about it is that all these savings are possible without compromising treatment quality,” he continued.

If you would like to benefit from the described workflow enhancements, it is probably worth giving universal excellence products from Kuraray Noritake Dental Inc. a try. For those who prefer to start with a single universal solution instead of transforming whole procedures immediately, the following feedback from clinicians may be enlightening.

UNIVERSAL CLEANER: SUITABLE EVEN FOR USE IN THE PATIENT’S MOUTH

The probably most special feature of KATANA™ Cleaner is its universal applicability. It cleans not only virtually every restorative material very well, but also works intra-orally to clean enamel and dentin after tooth preparation. Dr Richard Young from San Bernadino, CA, USA, uses it intra- and extra-orally, stressing that it “contains MDP based surfactant that breaks down blood and saliva – removing contamination.”

Fig. 3. Extra-oral application of KATANA Cleaner to remove contamination from a lithium disilicate crown by Dr Richard Young.

Fig. 4. Intra-oral application of KATANA Cleaner to remove contamination from the prepared tooth by Dr Richard Young.

UNIVERSAL ADHESIVE: SKIPPING THE WAITING TIME

Zero waiting time is probably the most striking feature of CLEARFIL Universal Bond Quick 2. While other universal adhesives need to be rubbed into any surface extensively, the product is applied within a few seconds. This reduces the risk of contamination and saves time. Based on his clinical experience, Dr Kendir confirmed that it works well: “In this case, CLEARFIL Universal Bond Quick 2 provided strong adhesion with minimal application time.”

Talking about universal adhesives in general, Dr Zorzin stressed that adhering to the protocols described in a material manufacturer’s instructions for use is particularly important: “Universal adhesives contain lots of different technologies in a single bottle. While this fact indeed allows users to rationalize their clinical procedures, it also requires some special attention. As every highly developed material, universal adhesives need to be used according to the protocols recommended by the manufacturer.” For CLEARFIL Universal Bond Quick 2, this protocol is particularly easy.

UNIVERSAL COMPOSITES: GREAT SHADE-MATCHING PROPERTIES

Lately, an experienced user of CLEARFIL MAJESTY™ ES Flow, Dr Michał Jaczewski from Legnica in Poland, tested the universal-shade option CLEARFIL MAJESTY ES Flow Universal – also in the low flowability variant. He confirmed that the reduced number of shades works well: The product “offers properties which are – from a personal perspective – ideal for the flowable injection technique. The shadematching properties are astonishing; the translucency is quite high when placed in thin layers (so that enamel is very well imitated), and the polishability is as good as that of CLEARFIL MAJESTY ES Flow. For virtually effortless, bubble-free injection, the product comes in a nicely designed syringe. And last but not least, the product’s mechanical properties provide peace of mind even in the posterior region.”

Fig. 5. Clinical image from the report of Dr Michał Jaczewski: Flowable composite injected into the transparent index.

Fig. 6. Clinical image from the report of Dr Michał Jaczewski: Central incisors beautifully restored.

According to Dr Jusuf Lukarcanin, MEDICANA International Hospital Izmir, Turkey, the same is true for the universal paste-type composite CLEARFIL MAJESTY™ ES-2 Universal. He states: “My first reaction to this material was: This is a Game-Changer. The results are magical. Smoother and easy handling properties, high-gloss, more natural light distribution and the process is simple. Aside from being able to skip the shade selection step, your workflow remains the same as with traditional composites. At first, I might have been a little sceptical about replacing all the different colours of composites we use in office every day. But after a couple of tries I found out that it indeed works every time, in some cases even without the use of a blocker. Simply ingenious!”

Fig. 7. Clinical image from Dr Jusuf Lukarcanin: Diastema closure in a 28-year-old female patient - initial clinical situation.

Fig. 8. Clinical image from Dr Jusuf Lukarcanin: Diastema closure in a 28-year-old female patient - upper anteriors treated with CLEARFIL MAJESTY ES-2 Universal in the shade UW.

UNIVERSAL RESIN CEMENT: NO PRIMER NEEDED

Primer for tooth structure, cement paste, ceramic primer and silane: PANAVIA™ SA Cement Universal has it all in a single syringe. With no extra bottles needed, it provides for streamlined cementation procedures. That is why Dr Devigus uses it as his standard solution for definitive placement of CEREC overlays and crowns: “It bonds to virtually every surface including lithium disilicate without a separate primer and offers a good flowability that facilitates restoration placement. An additional feature contributing to a quick and stress-free clinical procedure is its easy and gingiva-friendly excess removal after tack curing.”

Watch the video to hear what exactly Dr Alessandro Devigus says about PANAVIA SA Cement Universal:

CONCLUSION

Experience shared by clinicians from different clinical environments demonstrates that universal solutions can make restorative dentistry more efficient, predictable and economical. By reducing the number of materials, steps and technique sensitivities, universal products help streamline workflows while maintaining high clinical performance.

Smooth and efficient procedures, easy shade matching, and great clinical outcomes are key expectations in modern restorative dentistry. Kuraray Noritake Dental Inc. continues to support these needs through ongoing innovation in advanced dental materials. Building on the success of CLEARFIL MAJESTY™ ES Flow, with its multiple flowabilities and extensive shade range, a flowable composite with a simplified universal shade concept was developed.

Launched in Europe in 2025, CLEARFIL MAJESTY™ ES Flow Universal is available in two flowabilities – Super Low and Low. It is a highly filled flowable composite featuring submicron fillers (Super Low: 78% and Low: 75% by weight, respectively) and light diffusion technology.

Its universal shade system allows one shade (U) to cover the VITA classical A1-D4 system shades. For cavities in darker teeth (B3 and darker shades) with limited surrounding tooth structure – such as Class III and IV cavities – a second darker shade (UD) is available.

While the material is available in two flowabilities in Europe, Super Low is the variant offered in the United States and tested by the Dental Advisor.

CLEARFIL MAJESTY ES Flow Universal is gaining increasing clinical acceptance thanks to:

• A simplified two-shade concept
• Excellent handling properties
• High mechanical strength – comparable to paste-type composites
• Easy polishing and long-lasting gloss
• A well-designed syringe and tip system that helps minimise voids and dripping

DENTAL ADVISOR RESEARCH AWARD

Laboratory tests confirm strength, stability, and efficient placement

Independent in-vitro testing conducted at the Dental Advisor Biomaterials Research Center demonstrated that CLEARFIL MAJESTY ES Flow Universal (Super Low) delivers some of the highest physical property values within its class, including flexural strength, fracture toughness, and compressive strength.

The material also showed excellent shade matching across a broad range of tooth shades when compared with other universal-shade composites. Radiographic analyses further confirmed that the syringe and tip design contribute to minimal void formation, supporting reliable and efficient placement. Viscosity testing revealed a low-flow, no-slump consistency, allowing precise anatomical sculpting and controlled cusp build-up.

These results were key factors in earning the Dental Advisor Research Award, which recognizes outstanding physical property testing and a strong commitment to research-driven product development.

Dental Advisor Top Product Award

Clinicians praise handling, translucency, and blend-in ability

Beyond laboratory performance, CLEARFIL MAJESTY ES Flow Universal (Super Low) also excelled in clinical practice, which was a key factor in earning a Dental Advisor Top Product Award. Evaluators highlighted its ideal viscosity and impressive blend-in ability achieved through optimised translucency, light diffusion technology and fine-tuning of the chroma.

The simplified shade system and delivery design translated into confident, predictable results in daily practice, as reflected in evaluator feedback such as: "Excellent shade matching and no air bubbles." These attributes make the material well suited for a wide range of restorative applications in both anterior and posterior regions.

Scientific excellence and clinical practicality smartly combined

By receiving both the Dental Advisor Research Award and the Top Product Award, CLEARFIL MAJESTY ES Flow Universal (Super Low) demonstrates a strong balance of scientific excellence and clinical practicality. Its combination of simplified shade matching, high mechanical performance, and convenient handling makes it a versatile solution for clinicians seeking efficiency without sacrificing aesthetics or strength.

Part of Expanding Universal Excellence Portfolio

At Kuraray Noritake Dental Inc., we understand the demands of modern dental practices. Balancing complex procedures, tight schedules, and patient care is no easy task. That is why we have spent years refining our materials—so you can focus on what matters most: your patients.

Our Universal Excellence portfolio streamlines your workflows, offering you high-quality materials and tools that work seamlessly with your expertise.

CLEARFIL MAJESTY ES Flow Universal is the latest resin-based addition to our universal portfolio. Being suitable for a wide range of applications within direct and indirect restorative workflows, it is a valuable complement to existing universal paste-type composite CLEARFIL MAJESTY™ ES-2 Universal and universal resin cement PANAVIA™ SA Cement Universal.

For more information, visit Dental Advisor and the Kuraray Noritake Dental Europe website.

Today's dental practitioners are expected to deliver highly aesthetic, minimally invasive treatments that last – often within tighter schedules, with fewer assistants and under increasing financial and operational pressure. These factors can lead to elevated stress levels. With high patient expectations and a multitude of treatment options available, clinicians must make numerous decisions while the complexity of clinical procedures continues to increase.

Being aware of these dynamics and the associated challenges, Kuraray Noritake Dental Inc. has developed materials designed to make the clinician's work easier in many respects.

ADHESIVE DENTISTRY: OPPORTUNITIES AND CHALLENGES

To better understand this approach, let us take adhesive dentistry as an example. Being the driving force behind less invasive tooth preparations and the use of highly aesthetic tooth-coloured materials such as composites and ceramics, adhesive dentistry has significantly improved restorative dental care.

At the same time, the need to establish a strong and durable chemical bond between tooth structure and restorative material has made clinical procedures more complex than ever. Daily challenges include selecting the appropriate material and technique, preparing tooth structure correctly, controlling moisture and contamination, managing etching and pre-treatment protocols for each restorative material, and layering restorations predictably.

Intelligent simplification: Reducing complexity without compromising quality

The solutions Kuraray Noritake Dental Inc. has developed in recent years are materials that adapt to multiple indications, techniques and substrates – without adding procedural burden. The focus is not simply on innovation, but on meaningful innovation, leading to materials that genuinely streamline and simplify workflows.

While individual universal materials already offer flexibility, the thoughtful combination of compatible products can truly transform clinical procedures. When materials are designed to work together seamlessly, efficiency increases and variability decreases.

Universal product combinations from Kuraray Noritake Dental Inc. are designed to:

• Reduce the number of clinical steps
• Decrease technique sensitivity
• Improve workflow efficiency
• Simplify inventory management
• Reduce overall costs
• Support consistently high-quality treatment outcomes

The goal is not simplification for its own sake. Instead, the aim is to reduce complexity while maintaining the high performance required for predictable and durable clinical outcomes.

By aligning product features with proven clinical protocols, Kuraray Noritake Dental Inc. enables practices to work smarter, not harder.

Universal Excellence: product portfolio for simplified restorative procedures

The universal product portfolio of Kuraray Noritake Dental Inc. consists of five core products: The universal bond CLEARFIL™ Universal Bond Quick 2, the paste type composite CLEARFIL MAJESTY™ ES-2 Universal, the flowable alternative CLEARFIL MAJESTY™ ES Flow Universal, the universal resin cement PANAVIA™ SA Cement Universal and KATANA™ Cleaner as a universal cleaning solution designed for intra- and extra-oral use.

DENTAL ADVISOR HIGHLIGHTS THE SUITABILITY OF KATANA Cleaner FOR INTRA-ORAL USE

Clean surfaces – whether tooth structure or restorative materials – are essential for reliable and long-lasting adhesion in restorative dentistry. To achieve this, clinicians require a cleaning agent that removes contaminants such as blood or saliva efficiently and thoroughly, without adding complexity to the workflow. KATANA™ Cleaner was developed by Kuraray Noritake Dental Inc. to meet these clinical demands.

 
Recognized with a 2026 Research Award in the category Research – Restoration Cleaner, KATANA Cleaner is a truly universal cleaning solution for both restorations and tooth structure. Designed for intra-oral and extra-oral use, it contains MDP salt, which effectively removes contamination from a wide range of surfaces, supporting bond integrity during adhesive procedures.

 
Key benefits of KATANA Cleaner include:

• High cleaning efficacy based on the surface-active characteristics of MDP salt
• Mild pH value (4.5), allowing effective intra-oral application
• Simple, time-efficient application requiring just ten seconds of surface rubbing 

DENTAL ADVISOR RESEARCH AWARD: RECOGNITION FOR CLEAN SURFACES THAT SUPPORT OPTIMAL BOND STRENGTH

The Dental Advisor Research Team conducted in-vitro testing to evaluate the cleaning performance of KATANA Cleaner and its impact on bond strength with indirect restorative substrates. In these studies, zirconia and lithium disilicate surfaces were contaminated with saliva and subsequently treated with KATANA Cleaner. SEM analysis revealed virtually perfect surface cleanliness, which contributed to optimal bond strength levels. The Research Team also noted that KATANA Cleaner is “one of the few products commercially available that can be used intra-orally...”

SUITABLE SOLUTION FOR MANAGING CONTAMINATION

With its universal applicability, gentle yet highly effective cleaning effect and proven ability to restore optimal bond strength, KATANA Cleaner offers clinicians an excellent solution for managing contamination in adhesive dentistry. Its recognition with a 2026 Dental Advisor Research Award underscores its relevance and highlights its suitability for a wide range of indications.

PART OF EXPANDING UNIVERSAL EXCELLENCE PORTFOLIO

At Kuraray Noritake Dental Inc., we understand the demands of modern adhesive dentistry. Reliable adhesion depends not only on high-performing bonding materials, but also on proper surface preparation and contamination management throughout the workflow.

That is why KATANA Cleaner is part of our expanding Universal Excellence portfolio. Designed for both intra-oral and extra-oral use, it helps clinicians optimize adhesive procedures by efficiently removing contamination from tooth structure and restorative materials.

Supporting clean bonding surfaces in a simple and time-efficient manner, KATANA Cleaner complements restorative workflows involving products such as CLEARFIL™ Universal Bond Quick 2 and PANAVIA™ SA Cement Universal — contributing to predictable and durable adhesion across a wide range of clinical indications.

For more information, visit Dental Advisor at dentaladvisor.com.

I den moderna tandvården finns en stark efterfrågan på material som kombinerar smidig använding och effektivitet med estetiskt tilltalande och hållbara resultat. Sådana material gör det möjligt för tandvården att nå önskade resultat mera effektivt och frigör tid för det personliga mötet med patienten.

Vid behandlingar med direkta fyllningar har den resinkomposit man väljer stor betydelse för både hur smidig behandlingen är och kvaliteten på resultatet: Därför har en universalkomposit av pastatyp, som CLEARFIL™ MAJESTY ES-2 Universal (Kuraray Noritake Dental Inc.) blivit mycket populär. Med CLEARFIL™ MAJESTY ES Flow Universal, introducerar nu samma företag en fl ytande komposit med liknande egenskaper och du kan läsa om den nya kompositen i nedanstående frågesammanställning.

Hur kan du skapa vackra och hållbara ersättningar med fl ytande lätthet?

CLEARFIL™ MAJESTY ES Flow Universal är en fl ytbar komposit med två kompletterande nyanser. Den har designats för naturlig färmatchning och kan användas i många olika behandlingar. Produkten kombinerar praktiska flytbarhetsegenskaper med avancerad färgmatchningsförmåga och enastående mekaniska egenskaper.

Low

• Böjhållfasthet 151 MPa
• Tryckhållfasthet 373 MPa
• Fyllnadsgrad 75 wt/% / 59 vol%
• Radiopacitet 140 % AI

Super Low

• Böjhållfasthet 152 MPa
• Tryckhållfasthet 374 MPa
• Fyllnadsgrad 78 wt/% / 60 vol%
• Radiopacitet 150 % AI

Vad är CLEARFIL MAJESTY™ ES Flow Universal?

CLEARFIL™ MAJESTY ES Flow Universal är en ljushärdande, radiopak resinkomposit som är designad för att fungera i en mängd olika kliniska situationer. Den finns i två flyttbarheter och två nyanser. Den innehåller nanofillerteknologi för kontrollerad flytbarhet, beständigt putsresultat och naturligt vackra ersättningar. En smart kombination av emaljliknande translucens, dentinlik kroma och Light-Diffusion Technology (LTD) gör att kompositen smälter in perfekt bland omgivande tandvävnad. Den emaljliknande translucensen gör att ljuset kan passera genom materialet och förstärker den färgmässiga integreringen med omgivande tandstruktur. LDT gör att materialet bryts på ett sätt som efterliknar emaljens och dentinets naturliga ljusbrytning. Tillsammans med den finjusterade kroman bidrar de här egenskaperna till att materialet optiskt integreras till omgivande tandstruktur.

När kan du använda CLEARFIL MAJESTY™ ES Flow Universal?

Den här flytande kompositen är avsedd att använda i många olika situationer; från Klass I-V fyllningar till fissurförsegling och reparation och den är gjord för alla typer av behandlingar.

CLEARFIL MAJESTY™ ES Flow Universal kan användas för:

• Fyllningar av alla kavitetsklasser, cervikala skador (t.ex. rotkaries och v-formade defekter), tandslitage och tanderosion.
• Baseliner
• Injection moulding
• Korrigering av tandens form och position (t.ex. diastemaslutning och deformerade tänder) • Intraoral reparation av frakturerad protetik

Hur gör man färgtagningen?

Färgtagningen är verkligen mycket enkel när man använder CLEARFIL MAJESTY™ ES Flow Universal. De två kompletterande nyanserna, universal (U) och universal dark (UD) fungerar intuitivt - du behöver ingen färgskala. U passar för nästan alla posteriora och anteriora ersättningar. UD fungerar bäst när den önskade färgen är mörkare (B3 och mörkare) och där det finns lite kvar av tanden, som vid kaviteter av Klass III och IV. Du kan välja den nyans som fungerar bäst utifrån kavitetsklass och patientens ålder.

Färgmatchning med anteriora och posteriora restaureringar

Vilka faktorer bidrar till egenskaperna hos CLEARFILMAJESTY™ ES Flow Universal?

Formuleringen innehåller flera funktioner som syftar till klinisk effektivitet:

• Nanofillerteknologi: En optimerad fyllnadsgrad minskar krympning, ökar nötningsmotstånd och ger beständig ytglas.
• Universell färganpassning: Bra visuell integrering med omgivande tandstruktur gör färgtagningen väldigt smidig.
• Tixotropi: Flyter under appliceringen men är stabil när den väl är på plats, vilket underlättar precis applicering.

Varför ska jag välja CLEARFIL MAJESTY™ ES Flow Universal?

CLEARFIL™ MAJESTY ES Flow Universal gynnar dig genom:

• Pålitlig hantering och leverans
• Estetiska resultat både anteriort och posteriort
• Motståndskraftig mot nötning och ytdefekter
• Radioacitet som gör det enkelt att efterkontrollera
• Kan användas i en mängs olika behandlingssituationer

Hur används CLEARFIL MAJESTY™ ES Flow Universal?

Användingen är väldigt enkel och passar bra in i det vardagliga arbetsfl ödet:

1. Preparera och torrlägg området.
2. Applicera en kompatibel adhesiv (t.ex. CLEARFIL™ Universal Bond Quick 2).
3. Dispensera materialet med hjälp av sprutan och en fi n applikator.
4. Ljushärda enligt fabrikantens anvisningar (normal 20 sekunder, beroende på vilken nyans och vilken härdningslampa du använder).
5. Finishera och putsa ersättningen.

Att använda spruta gör att appliceringen blir både kontrollerad och bekväm.

Fyllning med CLEARFIL MAJESTY™ ES Flow Universal

Är CLEARFIL MAJESTY™ ES Flow Universal testad av oberoende källor?

Ja. CLEARFIL™ MAJESTY ES Flow Universal (Super Low) har testats av tandläkare genom tredjepartstestning och expertgranskad feedback. Nyligen fick produkten Research Award 2025 av The Dental Advisor. I den amerikanskbaserade tidskriften slog testpanelen fast:

“Testerna visar att den här kompositen har bland de högsta värdena avseende fysikaliska egenskaper bland de flytande kompositerna och den utmanar de starkaste kompositerna av pastatyp när det kommer till böj- och tryckhållfasthet och den har en idealisk radiopacitet.”

En mångsidig och fl ytande möjlighet: CLEARFIL MAJESTY™ ES Flow Universal

CLEARFIL MAJESTY™ ES Flow Universal är avsedd att underlätta restorativa behandlingar. Produkten kombinerar egenskaper som lättkontollerat handhavande, estetisk integration och mekanisk hållbarhet. Den kan vara ett praktiskt alternativ för tandläkare som vill ha en pålitlig, flytande komposit som passar för en lång rad behandlingar.

Lär dig mer >

Universal Excellence - Smarta och Smidiga lösningar

Vi på Kuraray Noritake dental Inc. förstår kraven inom den moderna tandvården. Att balansera komplicerade behandlingar, tajta scheman och patienterna behov är ingen enkel sak. Sedan decennier be nner vi oss därför på en ständig resa för att förenkla, förbättra och för na varje moment i ditt arbete. Vi har en tydlig målbild: en verklighet där material och verktyg fungerar smidigt tillsammans, där komplexiteten är minimerad och där du får tid att fokusera på det som betyder mest: varje patients individuella önskemål och behov. Det är framtidens tandvård och vi skapar den tillsammans.

Upptäck >

“Adding new value to dental care”

Few manufacturers can claim one century of innovation. However, as Kuraray celebrates its 100^th anniversary, its subsidiary, Kuraray Noritake Dental—shaped by this legacy—remains humble and focused on its holistic vision for improving the delivery of oral care.

Reflecting on this centenary, Satoshi Yamaguchi, president of Kuraray Noritake Dental, shares his perspective on how the company’s long-standing ethos continues to shape its direction. In this exclusive interview, he discusses Kuraray Noritake Dental’s latest solutions and the way the company combines scientific expertise with consistent quality, clear and evidence-based information, support grounded in everyday clinical needs, and a stable supply chain. The ultimate aim, Yamaguchi says, is to bring new value to dental care and contribute to more reliable and efficient clinical practice.

Mr Yamaguchi, could you tell us about your professional background and how you first joined Kuraray?

My Kuraray journey began with a strong aspiration to contribute to public health. I was drawn to the company’s extensive expertise in chemical manufacturing and the potential to apply its technologies in the medical field. I started in the medical development division, where I was involved in research and development activities. Later, I transitioned to a marketing role at Kuraray America and, upon returning to Japan, resumed my position in development. This allowed me to engage with the dental healthcare business from both a technical and a commercial perspective. Subsequently, I served as head of the dental business at Kuraray Europe in Germany, where I oversaw sales operations across the European region. These international experiences have profoundly shaped my professional approach, enabling me to lead with a global mindset and remain attuned to the specific needs of local markets.

How has this international experience shaped your approach as president of Kuraray Noritake Dental?

Through my international assignments, I came to recognise the importance of addressing the diverse values held across different countries and regions. In the field of dental materials, preferences often differ. In many parts of Europe and Asia, natural aesthetics are widely valued; in the US, treatment efficiency is often prioritised; and in South America, there is often an emphasis on balancing aesthetics with cost-effectiveness. Although these are general tendencies and can vary, they provide a useful guide in meeting the specific needs of each market.

Satoshi Yamaguchi, president of Kuraray Noritake Dental, previously served as head of Kuraray Europe’s dental business, based in Germany.

My goal is to establish a robust framework for delivering reliable, evidence-based information to dental professionals. We are striving to strengthen the foundation of trust by facilitating the collection of credible data and case studies from both internal and external sources, ensuring that the information we provide contributes to greater confidence in clinical practice. In addition, we place strong emphasis on how this information is communicated. By leveraging multiple channels—presentations at academic conferences and seminars, contributions to journals and communication through digital platforms, for example—we are creating an integrated system that ensures our messages reach dental professionals effectively.

How does Japan’s role as a dental innovation hub influence the company’s global operations?

In Japan, there is a focus on creating scientifically proven technologies and transforming them into trusted dental solutions. At Kuraray, a prime example is our original adhesive monomer, MDP. This solution exhibits exceptional bond strength, even when using traditionally difficult substrates such as metals and zirconia. Today, MDP is recognised as a proven global standard in adhesive monomers and is widely used by dental material manufacturers around the world.

Scientifically valid technologies developed in Japan are being utilised in clinical settings worldwide, supported by reliable, evidence-based information. This tradition is a driving force behind Kuraray Noritake Dental. We honour it by prioritising materials that can function like natural tooth substances over the long term in the oral environment—ensuring clinical reliability through durability, defined as the preservation of strength and aesthetics. Building on this foundation, we continuously enhance the value of our products by expanding indications and improving usability.

How important is the European market in your overall strategy?

The European market plays a vital role in advancing our efforts in quality assurance and information dissemination. Given the strictly enforced medical device regulations and environmental laws, we proactively work to enhance quality and reliability in our operations in the region, including in the areas of product design, packaging and product information. In turn, these initiatives help to improve the accuracy of product development and information dissemination for all markets.

At the same time, we are strategically expanding our global business operations, focusing on the US, Asia and South America. To ensure the consistent delivery of high-quality products and services, we are working in close collaboration with local dental professionals, educational institutions and partner companies. By leveraging the expertise gained through our operations in Europe and adapting this to the unique needs and cultures of other regions, we continue to provide reliable solutions for dental professionals worldwide.

Kuraray Noritake Dental introduced several new materials last year. What can you tell us about these materials and the clinical needs they were designed to meet?

At the 2025 International Dental Show, we introduced CLEARFIL MAJESTY ES Flow Universal, CLEARFIL Universal Bond Quick 2 and CERABIEN MiLai. These products are based on our concept of Universal Excellence, a philosophy that emphasises scientifically grounded performance and outcomes.

Dental practitioners in clinical settings seek materials that they can use with confidence. To meet these needs, we ensured that these materials embody the principles of Universal Excellence. This means versatile, high-performance solutions that streamline clinical workflows by minimising the number of required components and procedural steps. In this way, the products support decision-making in daily dental practice and laboratory work.

KATANA Zirconia is recognised for aesthetics and strength. What sets your proprietary zirconia powder and multilayer technology apart in today’s competitive CAD/CAM market?

We consistently develop and manage raw material powders in-house. By focusing on proprietary material development, we have created high-quality dental zirconia that combines aesthetics and mechanical strength. In addition, our advanced manufacturing technologies and strict quality control standards ensure stable and reliable product quality. Furthermore, by utilising our proprietary zirconia powder and working closely with manufacturers of milling machines and sintering furnaces, we have significantly reduced both processing and sintering times in the fabrication of zirconia restorations.

One notable example is KATANA Zirconia ONE SPEED CROWN, which supports a streamlined chairside workflow. We have developed a new zirconia powder that can reach a highly activated state with little energy. This accelerates the sintering process, thereby achieving an ultra-short sintering time of just 9 minutes. Furthermore, our zirconia and multilayer technology enable natural gradation by varying both shade and translucency across the layers of the zirconia disc—closely replicating the appearance of natural teeth. In KATANA Zirconia YML, each layer contains a different concentration of yttria: the upper layers offer natural colouration and high translucency, and the lower layers deliver superior strength. Owing to this advanced material design and multilayer technology, the KATANA Zirconia series combines outstanding aesthetics and mechanical performance and contributes to greater efficiency in clinical workflows.

Kuraray has regional offices in China and Brazil. How do you adapt product development and clinical education to the diverse needs of these fast-growing markets?

China and Brazil are two of the world’s fastest-growing dental care markets, characterised not only by their large populations but also by a growing interest in quality dental care, rapidly advancing adoption of CAD/CAM technologies and ongoing development of clinical dental education. We address these evolving needs by delivering products and clinical support tailored to the specific dental requirements and educational styles of each country.

For example, we continue to meet the demand for our adhesive dental materials—such as the CLEARFIL and PANAVIA series—by offering hands-on seminars and webinars in local languages. By sharing clinically relevant information backed by scientific evidence, we contribute to improving the quality of local dental care.

In addition, user feedback gathered through our local offices serves as a valuable source of insight for product development. By incorporating market-specific trends, preferences in product handling and differences in clinical education styles into the development of new products, we can deliver locally optimised quality solutions.

Kuraray Noritake Dental is expanding production at its new plant in Miyoshi in Japan. How will this affect supply chain resilience and product innovation?

Leading up to this year, we significantly strengthened our global supply system for dental materials. At the heart of this initiative was the strategic expansion of production capacity at our Miyoshi plant, where we ultimately aim to roughly double production capacity. This facility specialises in the manufacturing of inorganic dental materials such as zirconia and porcelain and plays a critical role in our business strategy through technological expertise, rigorous quality control and product development capabilities.

Additionally, by strengthening collaboration between our manufacturing site and our research and development, we are working to establish a system that enables rapid incorporation of feedback from clinical settings into product improvements. These efforts also contribute to enhancing our product development capabilities, allowing us to deliver dental material products that meet market needs in a timely manner. We view this as a vital step towards better meeting the expectations of dental professionals worldwide and elevating our market presence.

As the Kuraray Group marks its 100^th anniversary, what vision is Kuraray Noritake Dental pursuing for the future of dental care?

Our anniversary presents an opportunity to reflect on the spirit that has shaped the company over the last 100 years. At the heart of our company lies a philosophy of embracing challenges: “For people and the planet—to achieve what no one else can”. Long before the term “corporate social responsibility” became widespread, we were addressing social issues through the power of technology and developing materials that improve lives. That ethos continues to underpin our business today.

Since entering the dental industry as a chemical products manufacturer, we have remained committed to craftsmanship and quality. As noted earlier, because dental materials are used inside patients’ mouths over extended periods, we consider durability to be a particularly critical factor. This durability encompasses strength and aesthetics, which together form the foundation of reliable clinical performance.

However, even products backed by advanced technology may not fully convey their intrinsic value to users. That is why we strive to provide reliable, evidence-based information and deliver trusted products to clinical settings.

What can you tell us about future initiatives at the company?

Through collaborative product development with dental clinicians, we aim to incorporate more insights from the front lines of dental care. By actively listening to dental professionals and technicians, we aim to further address the real-world challenges that they face and deliver products that more effectively meet daily clinical demands. We also aim to build greater trust with dental clinicians by sharing reliable, evidence-based information and clearly communicating the scientific evidence and development background behind our products. Additionally, in support of our commitment to sustainability, we aim to offer responsible choices to users through designing products with environmental considerations in mind and reducing our overall environmental impact.

Through these initiatives, we will continue adding new value to dental care by leveraging our material design expertise, which is rooted in the founding spirit of our company. We aspire to remain a trusted partner for dental professionals around the world—one that they can rely on with confidence.

Originally published on Dental Tribune website on March 4^th, 2026.

INTRODUCTION

Adhesive dentistry has seen significant advancements over the past decades. Initially, dental adhesives evolved from no-etch systems to etch-and-rinse systems, which consisted of multiple components. From then on, manufacturers shifted focus toward simplifying the procedure. Different generations of self-etch adhesives and, finally multi-mode or universal adhesives were the result. The latter category, introduced in the early 2010s, nowadays comprises numerous products offered by many different manufacturers.

In general, universal adhesives offer more procedural freedom and simplicity than multi-step, multi-bottle systems as well as good adhesion. According to a recent review¹, adhesive properties have improved and manufacturers have also succeeded in reducing the technique sensitivity of the adhesive systems. However, hybrid layer degradation still seems to be a relevant issue for many modern products available on the market. Moreover, feedback from clinicians reveals that there are several areas of concern where bonding systems in general can be improved. These include the risk of contamination due to a lengthy procedure or the need for rubbing, pooling of the adhesive in corners and accumulation along margins. Moreover, some adhesives are challenging to introduce into narrow cavities, while their curability may be limited.

That is why Kuraray Noritake Dental Inc. decided to develop a new-generation universal adhesive that addresses these areas of concern: CLEARFIL™ Universal Bond Quick 2. This latest evolution in dental bonding technology is based on decades of knowledge in the development of clinically successful dental adhesives at Kuraray Noritake Dental Inc. It retains all the benefits of its predecessor – the current extensively tested and clinically proven CLEARFIL™ Universal Bond Quick – adding higher strength and improved handling.^2-5

THE ESSENTIAL BENEFITS OF CLEARFIL Universal Bond Quick 2

CLEARFIL Universal Bond Quick 2 offers the following essential benefits:

• Quick and straightforward application procedure
• High-strength bonding layer
• Consistently durable bond
• Ease of application
• Minimised risk of pooling
• Procedural freedom
• Immediate availability for clinical use

For all those who wonder how the improvements were implemented, which technologies are responsible for them and whether there is scientific proof, the following paragraphs are worth reading. They summarize essential general knowledge about adhesive formulations, explain potential issues and their causes, and address every benefit featured by CLEARFIL Universal Bond Quick 2, explaining all the important details around it.

KEY COMPONENTS OF UNIVERSAL ADHESIVES

Universal adhesives are based on highly complex formulations with many different constituents and technologies combined in a single bottle. The most essential parts found in virtually every universal adhesive are:

RESIN COMPONENTS

Just like composite restorative materials, dental adhesives are resin-based materials. This means that different kinds of cross-linking and functional monomers are the beating heart of the formulation. Functional monomers are initially hydrophilic and form linear polymers upon curing, while cross linking polymers are hydrophobic and form stronger, highly cross-linked polymer networks.⁶ They are added to adhesive formulations to fulfil different tasks: some monomers are used to promote adhesion to tooth structure or composite resin, while others are used as etching or demineralizing agents, wetting enablers, and agents promoting penetration into the tooth structure. Hence, they have an impact on application properties, bond strength to various substrates including enamel and dentin, strength, hydrolytic stability and overall durability of the bonding layer, and more.

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References

1. Breschi L, Maravic T, Mazzitelli C, Josic U, Mancuso E, Cadenaro M, Pfeifer CS, Mazzoni A. The evolution of adhesive dentistry: From etch-and-rinse to universal bonding systems. Dent Mater. 2025 Feb;41(2):141-158.
2. Jaggi M, Karlin S, Zitzmann NU, Rohr N. Shear bond strength of universal adhesives to human enamel and dentin. J Esthet Restor Dent. 2024 May;36(5):804-812.
3. Peumans M, Vandormael S, De Coster I, De Munck J, Van Meerbeek B. Three-year Clinical Performance of a Universal Adhesive in Non Carious Cervical Lesions. J Adhes Dent. 2023 Jun 8;25(1):133-146. doi: 10.3290/j.jad.b4186751. PMID: 37387551.
4. de Almeida RAM, Lima SNL, Nassif MV, Mattos NHR, de Matos TP, de Jesus Tavarez RR, Cardenas AFM, Bandeca MC, Loguercio AD. Eighteen-month clinical evaluation of a new universal adhesive applied in the “no-waiting” technique: a randomized clinical trial. Clin Oral Investig. 2023 Jan;27(1):151-163. doi: 10.1007/s00784-022-04703-7. Epub 2022 Sep 6. PMID: 36068369; PMCID: PMC9447982.
5. De Almeida R, Siqueira F, Verde T, Naupari-Villasante R, Reis A, Loguercio AD, Cardenas A. Prolonged application time effects on universal adhesives in non-carious cervical lesions: An 18-month split mouth randomized clinical trial. J Dent. 2024 Jan;140:104800. doi: 10.1016/j.jdent.2023.104800. Epub 2023 Dec 4. PMID: 38056759.
6. Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, Coutinho E, Suzuki K, Lambrechts P, Van Meerbeek B. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials 2007; 28(26):3757-85.

REDEFINING WHAT “UNIVERSAL”  MEANS

When discussing the universal properties of a dental adhesive, most of us probably think of its compatibility with various etching techniques (from self-etch to total-etch) and a wide indication range. After all, universal adhesives are typically used as bonding agents for direct restorations made of light-curing composite, for immediate dentin sealing, for repair procedures and also in the context of indirect restoration placement.

However, in our opinion, there is more to it:

This means it should be compatible with any resin-based composite and self-adhesive resin cement, regardless of the manufacturer.

BREAKING FREE FROM SYSTEM BOUNDARIES

This is not self-evident: For a long time, “staying within the manufacturer’s own system ” has been a key prerequisite for the successful use of dual-cure core build-up materials and self-adhesive resin cements. Manufacturers worldwide have strongly recommended combining components from the same manufacturer and system to provide for chemical compatibility, optimal alignment, and the best possible outcomes. 

CLEARFIL™ Universal Bond Quick 2: FREEDOM AND FLEXIBILITY

With the new CLEARFIL™ Universal Bond Quick 2, this is no longer necessary: The R&D team of Kuraray Noritake Dental Inc. in Japan has developed an adhesive that works well not only with the company’s self-adhesive resin cement PANAVIA™ SA Cement Universal, but also with other manufacturers’ products. The same applies to core build-up materials: Compatibility is no longer limited to CLEARFIL™ DC CORE PLUS, but extends to solutions offered by other companies. Thorough testing has confirmed that it works well – provided each product’s official instructions for use are followed.

ONE ADHESIVE FOR EVERY CHALLENGE

This makes CLEARFIL Universal Bond Quick 2 a truly universal adhesive and, in fact, the only one needed in your dental practice. Interested? Learn more about the product and its innovative features, including its effortless application with no waiting time. 

SMART. STREAMLINED. UNIVERSAL.

At Kuraray Noritake Dental Inc., we understand the demands of modern dental practices. Balancing complex procedures, tight schedules, and patient needs is no easy task. That is why we have been on a relentless journey to streamline, enhance, and refine every step of your work for decades. Our vision is clear: a world where your materials and tools work seamlessly in your hands, where complexity is minimized, and where you are given enough time to focus on what matters most: the individual desires and needs of every single patient. This is the future of dentistry, and together, we’re making it happen.

We invite you to explore our comprehensive Universal Excellence portfolio —  from bonding agent to composites and resin cement. For Smart Streamlined Solutions in your practice.

DENTAL ADVISOR 2026 AWARDS RECOGNISING KURARAY NORITAKE PRODUCTS FOR EXCELLENCE AND RELIABILITY

As clinical demands continue to rise and chairside time becomes increasingly precious, dental professionals are nowadays looking for materials and devices that truly deliver in daily practice – while demanding less of themselves. In this context, efficiency, ease of use and long-term performance have become decisive factors in product selection.

In a market characterized by frequent product introductions and bold claims, however, identifying the most suitable solutions can be challenging. A useful guide to well-founded decisions: Independent evaluations that combine rigorous laboratory testing with real-practice clinical assessments. One of the most trusted institutions offering this kind of evaluations in the Dental Advisor. Once per year, this respected authority in dental product testing publishes its Top & Preferred Product and Research Awards – highlighting those products that stand out not only for innovation, but for proven, consistent performance.

In 2026, several solutions from Kuraray Noritake Dental Inc. were recognized – ranging from a new universal flowable composite to long-established materials that continue to define modern restorative and adhesive dentistry.

A PROMISING BLEND OF CHARACTERISTICS: RESEARCH AWARD WINNERS

According to Dental Advisor, “Companies that receive Research Awards demonstrate a commitment to advancing dental technology and enhancing patient care.” Product properties are tested in the Dental Advisor Biomaterials Research Center to evaluate the scientific performance and identify those materials with the most promising blend of characteristics.

1. CLEARFIL™ Universal Bond Quick 2 (Research Award and Preferred Product)

Launched in 2025, CLEARFIL™ Universal Bond Quick 2 is an enhanced version of the popular multi-mode adhesive CLEARFIL™ Universal Bond Quick. Both stand out due to their minimal application time. Research conducted at the Dental Advisor Biomaterials Research Center demonstrated excellent bond strength to enamel and dentin, even after artificial aging and saliva contamination. The latter indicates a consistent performance even in wet environments like the oral cavity. The in-vitro tests also confirmed a thin film thickness (3-5μm), supporting accurate seating of indirect restorations.

2. CLEARFIL MAJESTY™ ES Flow Universal (Research and Top Product Award)

CLEARFIL MAJESTY™ ES Flow Universal is a highly filled flowable composite launched in 2025. It features submicron fillers (78% by weight) and a simplified universal shade system enabled by light diffusion technology. Independent testing in the Biomaterials Research Center of the Dental Advisor confirmed that it delivers some of the highest strength values in its class, along with excellent radiopacity and great shade matching compared with other universal-shade composites. Designed for efficient placement, its syringes and application tips help minimize voids, a benefit confirmed by radiographic analysis of filled syringes and attached tips after dispensing of material. Viscosity testing reveals that the material offers a low-flow, no-slump consistency that allows precise cusp build-up and detailed anatomical sculpting. While the material is available in two flowabilities (Low and Super Low) in Europe, Super Low  is the variant offered in the United States and tested in the Dental Advisor Biomaterials Research Center.

3. KATANA™ Cleaner

KATANA™ Cleaner became a 2026 Research Award winner without prior clinical evaluation. The universal cleaning agent contains MDP salt, designed to effectively remove contaminants from both restorative materials and tooth structure. Laboratory testing by the Dental Advisor demonstrated that it restores bond strength on saliva-contaminated zirconia and lithium disilicate to optimal levels, with SEM analysis confirming nearly complete surface cleanliness. In its summary of research highlights, the Dental Advisor team stressed that KATANA™ Cleaner is one of the few commercially available cleaners approved for intraoral use.

4. PANAVIA™ Veneer LC (Research Award and Preferred Product)

PANAVIA™ Veneer LC is widely recognised for delivering strong, durable bonding and highly aesthetic outcomes in veneer procedures. Laboratory testing revealed that, when used with the US-recommended components – PANAVIA Veneer LC Paste, CLEARFIL™ Universal Bond Quick and CLEARFIL™ Ceramic Primer Plus – the system maintains a high bond strength even after artificial aging. This performance was consistent across multiple substrates, including enamel, dentin, silica-based ceramics (lithium disilicate) and zirconia. Furthermore, the system outperformed two other leading veneer cements in gloss retention and wear resistance.

TOP PRODUCT AWARD WINNERS

Top Products are “exceptional products [that] have consistently demonstrated their excellence and reliability, earning a lasting place in our publication“. The winners are selected based on laboratory testing and clinical evaluations conducted under real-life conditions: “Our dedicated volunteer evaluators provide unbiased insights from their real-world experiences, ensuring that only the very best receive this prestigious accolade”, as stated on www.dentaladvisor.com.

1. CLEARFIL MAJESTY™ ES Flow

A proven favourite, CLEARFIL MAJESTY™ ES Flow earned a Top Award for the 10^th time(!), reaffirming its position as a leading product in the direct restoratives category (Composite: Highly Filled Flowable). Recognized for its excellent handling, ease of use, and true-to-life aesthetics, it remains a trusted choice for clinicians seeking versatility and consistently high-quality results. Aesthetic properties were highlighted by one of the evaluators as follows: "The material blended so well with the tooth structure that you had to look hard to find the interface." 

2. CLEARFIL MAJESTY™ ES Flow Universal (Research and Top Product Award)

This product not only excels in the laboratory setting, but also in the practice environment. Among the top features highlighted clinically are its ideal, non-slumping consistency, optimised translucency and great blend-in ability supported by light-diffusion technology. The blend-in ability, along with the benefits resulting form the delivery system, are reflected in a comment: “Excellent shade matching and no air bubbles.”

3. CLEARFIL™ SE Protect

CLEARFIL™ SE Protect continues to set the standard among self-etch adhesives, combining antibacterial properties with fluoride release. Backed by a strong history of clinical success, it received a Top Award this year for its outstanding bonding performance and long-term reliability, making it a key component in modern restorative dentistry. An evaluator commented: "The gold standard in bonding to reduce post operative sensitivity."

4. PANAVIA™ SA Cement Universal

Designed for straightforward and dependable self-adhesive cementation, PANAVIA™ SA Cement Universal earned a Top Award for its high-quality bonding to a wide variety of substrates – without the need for additional primers. Its user-friendly handling and predictable outcomes make it a popular choice for clinicians who value both efficiency and performance. Evaluators highlighted its moisture tolerance as well as its "Amazing viscosity, tack cure-ability and very easy cleanup."

5. TEETHMATE™ DESENSITIZER

Awarded a Top Award for the nineth consecutive year, TEETHMATE™ DESENSITIZER continues to stand out for its exceptional effectiveness in managing hypersensitivity. This non-invasive solution remains highly regarded for delivering durable, long-lasting relief from sensitivity. Its long-lasting effect was confirmed in a comment: “At six months, the majority of patients continue to experience marked improvement from their pre-operative sensitivity or no sensitivity at all."

PREFERRED PRODUCT AWARD WINNERS

According to www.dentaladvisor.com, “The Preferred Product Awards highlight those items that not only excel in performance but also resonate with the needs of dental practitioners.“ Products are selected for this award based on clinical evaluations and in-vitro test results, and a preferred feature is always highlighted.

1. CLEARFIL™ Universal Bond Quick 2 (Research Award and Preferred Product)

Apart from winning a Research Award, CLEARFIL™ Universal Bond Quick 2 became a Preferred Product mainly for its rapid working time, enabled by a formulation with a unique blend of proven and new monomers. It allows clinicians to apply the adhesive and begin working instantly – a feature that is very well received by the consultants: "Extremely quick application time that allowed me to get right to work. Every time saving ability is ideal." Film thickness is low and application extraordinarily easy.

2. CLEARFIL™ CERAMIC PRIMER PLUS

The fact that it is a versatile, one-step solution made CLEARFIL™ CERAMIC PRIMER PLUS become a Preferred Product in the category Indirect Restoratives – Universal Primer once again. An evaluator was particularly happy that it is “Easy to use on a variety of materials”.  While highly versatile in application, the product also stands out for delivering exceptional bond strength – especially when applied to silica-based ceramics, zirconia, and composites. Its proven performance has made it a trusted choice among clinicians around the world.

3. PANAVIA™ Veneer LC (Research Award and Preferred Product)

PANAVIA™ Veneer LC’s preferred feature is its excellent handling, as stated by the evaluators. They liked to apply and model it, as it offered the desired combination of flowability, stability, viscosity and non-stickiness. While matching try-in pastes were well-received, one evaluator particularly highlighted the opacity of the white shade: "The white shade of the cement was opaque enough for efficient masking of discolored
tooth structure."

A SHARED FOCUS ON IMPROVING PATIENT CARE

At Kuraray Noritake Dental Inc., innovation is guided by a clear understanding of clinical realities. The awards received in 2026 reflect an ongoing commitment to developing materials that balance scientific excellence with practical usability – supporting predictable outcomes, efficient workflows and improved patient care. As dentistry continues to evolve, the recognition from the Dental Advisor underscores the importance of solutions that stand the test of time. By listening closely to clinicians and investing continuously in research and development, Kuraray Noritake Dental Inc. remains focused on advancing dental science in ways that matter most – supporting dental professionals in their striving for success and for enhancing their patients’ quality of life, every day.