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CLEARFIL™ SE Protect: A uniquely antibacterial adhesive system

In the early 1990s, Kuraray introduced CLEARFIL™ LINER BOND 2, the first self-etching adhesive, to the world. Among the products that this system has led to is the award-winning CLEARFIL™ SE Protect, which was introduced in 2004 and remains highly valued by dental professionals across the world. By combining Kuraray Noritake Dental’s famed original MDP monomer with the antibacterial 12-methacryloyloxydodecylpyridinium bromide (MDPB) monomer, this self-etching adhesive is able to kill bacteria on contact. How is this possible? Let’s find out.

 

Pyridinium holds the key

 

The crucial element that provides CLEARFIL™ SE Protect with its antibacterial cavity cleansing ability is contained in the MDPB monomer. The pyridinium group in this monomer is positively charged, whereas the cell structures of bacteria are, generally speaking, negatively charged. This means that they are automatically attracted to the positively charged contact points of the MDPB monomer, causing these bacteria cell membranes to lose their electrical balance and be destroyed. This process—bacteriolysis—kills the bacteria.

 

The bactericidal mechanism of MDPB is presumed to be similar to that of the well-known antibacterial agent cetylpyridinium chloride, which is in many toothpastes and mouthwashes.

 

Certified biocompatibility

 

The MDPB monomer is immobilised during the polymerisation of the bonding and remains latently active without affecting the dental patient’s own cells. Unlike the situation when other cavity hygiene products are used, this process—patented by Kuraray Noritake Dental—does not have a negative impact on the bond strength and even ensures that there are no long-term cytotoxic effects on the patient’s own body cells such as odontoblasts. These results have been confirmed by the official biological evaluation for medical devices known as the ISO 10993 series.

 

Award-winning results with CLEARFIL™ SE Protect

 

With its antibacterial effect, high bond strength to enamel and dentine and long-term fluoride release, CLEARFIL™ SE Protect is reliable, versatile and future-proofed. This tried-and-tested two-step self-etching bonding system is fast and easy to use for direct restorations. For bonding indirect restorations and core build-ups, simply mix it with Kuraray Noritake Dental’s CLEARFIL™ DC Activator according to the instructions for use.

 

 

Thanks to its combination of MDP and MDPB monomers, CLEARFIL™ SE Protect leads to predictable, durable restorations—and it has received plenty of accolades from dental experts as a result. In 2022, this adhesive again received a Top Product Award in the Direct Restoratives, Bonding Agent: Self-Etch category from DENTAL ADVISOR. This was the fourth year in a row that it earned such recognition, and in addition, the 13 DENTAL ADVISOR consultants and editors gave CLEARFIL™ SE Protect a stunning 98% overall clinical rating.

 

HIGHLIGHTS september 2022 (LV)

 

PANAVIA Veneer LC inovatīvā tehnoloģija

Šajā "Highlights" tiek aprakstītas tehnoloģijas un tas, kā tas sekmē jaunā PANAVIA Veneer LC daudzās priekšrocības

 

 

 

PANAVIA™ cements

Testimonial article by Dr. Troy Schmedding, USA

 

From PANAVIA™ EX to PANAVIA™ V5, Kuraray Noritake Dental Inc.‘s flagship product line of cements continues to evolve to offer reliable adhesion, enhanced ease of use, and superior esthetics.

 

Dentistry has certainly evolved in the years since Kuraray Noritake Dental Inc. developed the phosphate monomer MDP. But over the past 4 decades, it has rooted itself in restorative dentistry as the tried-and-true ingredient that clinicians rely on for strong adhesion to tooth structure as well as metals and zirconia. MDP is a key ingredient in the manufacturer’s flagship PANAVIA™ line of cements, which continues to evolve in line with a growing variety of indirect restorative materials from which to choose.

 

One example of this evolution is PANAVIA™ SA Cement Universal, one of the first true universal self-adhesive resin cements to hit the market. In addition to the original MDP monomer, it incorporates the LCSi monomer, a silane-based carbon chain in a dual-barrel system that forms a chemical bond with glass and ceramic materials.

 

“PANAVIA™ SA Cement Universal allows you to achieve a strong bond no matter which substrate is being used.”

- Troy Schmedding, DDS –

 

A STRONG BOND THAT’S SIMPLE TO CREATE

 

But all chemistry aside, what’s in it for the clinician? As dental educator and author Dr. Troy Schmedding points out, the key benefit of PANAVIA™ SA Cement Universal is eliminating the confusion over how to treat different substrates. This is because the material adheres to virtually every material without the need for a separate primer. “The plus side for the practitioner is that the confusion of ‚how do I condition zirconia‘ or ‚how do I condition glass ceramics‘ is no longer an issue because the paste formulation allows you to achieve a strong bond no matter which substrate is being used - whether it is the MDP monomer allowing strong adhesion to zirconia or the LCSi monomer forming a chemical bond with glass ceramics,” he shared.

 

DIALING UP THE AESTHETICS

 

Kuraray Noritake Dental Inc. considers PANAVIA™ V5 the most esthetic cement it has ever created. Available in 5 shades - White, Brown, Universal, Clear, and Opaque – it took researchers over 10 years to develop and features an anime-free catalyst that allows for superior colour stability and improved bond strength to dentin. And like its predecessors, PANAVIA™ V5 offers a simple cementation procedure that is compatible with all indications, from crown-and-bridge and implant abutments to ceramic inlays and laminate veneers.

 

“Kuraray Noritake Dental Inc. has an incredibly strong reputation in adhesive dentistry, so it should offer clinicians a lot of comfort and flexibility to partner with not only a reputable company, but one that continues to research and evolve their key products,” concluded Dr. Schmedding.

 

Dentist:

DR. TROY SCHMEDDING, DDS
USA

 

Article from Dental product shopper, vol. 14 No. 5

 

Jaunais PANAVIA Veneer LC šļirces dizains

Nodrošiniet augstu uzklāšanas kontroli, izmantojot jauno šļirci un uzgali!
Īpašais PANAVIA Veneer LC šļirces un uzgaļa dizains nodrošina vieglu materiāla izspiešanu un uzklāšanas kontroli. Attēlā tālāk parādītas jaunās funkcijas

 

 

 

Work flow PANAVIA Veneer LC with PANAVIA V5 Tooth primer

Minimally invasive procedures using highly aesthetic restorations is what patients expect when they seek restorative treatment. With the various types of restorations available today, it is possible to meet these expectations – provided that the right materials are used.

 

For the placement of veneers, a resin cement must be selected that supports long-lasting aesthetics, is easily applied, offers a working time sufficient for simultaneous cementation of multiple restorations and provides excellent bond strength. The new “PANAVIA™ Veneer LC” is precisely what you need.

 

What is the workflow you ask? Check out the video to see the full workflow using PANAVIA V5 Primer and CLEARFIL Ceramic Primer Plus.

 

 

Excess removal with PANAVIA Veneer LC

One of the key features when talking about cements is the ease of removal of excess cement. Our newest cement - PANAVIA™ Veneer LC - offers the ideal paste consistency, a low film thickness and long working time.

 

But how about excess removal? Do you wonder how do we compare to other similar products?

 

Check out this video demonstrating an excess removal comparison between PANAVIA Veneer LC and other brands.

 

 

Dr Jorge Espigares on PANAVIA Veneer LC

Webinar recording Panavia Veneer LC - Dr Jorge Espigares

PANAVIA™ Veneer LC

Great solution for challenging task

PANAVIA™ family just got bigger! We are introducing the new PANAVIA™ Veneer LC – the specialist cement that offers aesthetics, excellent paste viscosity, easy handling and 200 seconds(!) working time under ambient light (8000 lux.). Coming in four different shades with matching try-in pastes from PANAVIA™ V5 system, it allows users to take into account the individual shade requirements and deliver highly aesthetic outcomes when cementing veneers, inlays and overlays.

Join our free webinar now and be the first to learn all the details about this new and exciting product from Kuraray Noritake Dental Inc..

 

 

 

 

ABOUT DR JORGE ESPIGARES, DDS, PHD

Dr. Jorge Espigares received his DDS degree at the Faculty of Dentistry, University of Granada in Spain and obtained his PhD degree under the supervision of Prof. Tagami at Tokyo Medical and Dental University in Japan. Specialized in Cariology and Operative Dentistry, Dr. Jorge Espigares has clinical experience in Spain and UK, and has authored and coauthored full-length research publications with his colleagues at TMDU.

 

Clinical Report about PANAVIA Veneer LC

PRESENTATION OF A STUDY WITH ILLUSTRATIVE CASES

by Dr. Yohei Sato, DMD, PhD and Dr. Keisuke Ihara, CDT.

 

INTRODUCTION

 

In recent years, the application and advancement of digital technology in dentistry has made it possible to accomplish the fabrication of highly accurate prosthetic zirconia appliances that were difficult to mill using the previously available technology. In addition, thanks to advances in adhesive dentistry and the advent of cements that bond strongly to a diverse range of materials, cements have come into wide clinical use that can cope with the many types of materials used for the fabrication of prosthetic appliances.

 

At our hospital, we select the treatment method most suitable for each case by appropriately specifying various types of prosthetic appliance according to the status of each case. For example, we may specify zirconia prosthetic restorations fabricated by the CAD/CAM system, or silica-based ceramic prostheses, or those made of lithium disilicate glass, as the case dictates.

 

PANAVIA™ V5 is a resin cement system that bonds strongly to various types of prosthetic appliance, as well as to tooth structure. PANAVIA™ Veneer LC, a new resin cement system developed by Kuraray Noritake Dental Inc., has suitable characteristics for bonding laminate veneers, using two types of primer that can be used in common with PANAVIA™ V5. Here are some clinical examples of its advantages as a resin cement system used for laminate veneers restorations.

 

 

PANAVIA Veneer LC - CIETĒŠANAS TEHNOLOĢIJA

INOVATĪVA CIETĒŠANAS TEHNOLOĢIJA
PANAVIA™ Veneer LC nodrošina gaismā cietējošu cementu, apvienojot vairākas tehnoloģijas, nodrošinot augstāko iespējamo adhēziju.

VIRSMAS HERMETIZĀCIJA
Modificētā skāriencietināšanas tehnoloģija tiek izmantota, lai sasniegtu ilgāku apstrādes laiku, vienlaikus nodrošinot PANAVIA™ izslavēto adhēziju. PANAVIA™ Veneer LC, apvienojumā ar PANAVIA™ V5 Tooth Primer nodrošina gaismā cietējošajam cementam būtisku ķīmisko elementu. PANAVIA™ V5 Tooth Primer ir paškodinošs zoba audu (emaljas un dentīna) praimeris kas droši hermetizē zoba adhezīvo virsmu, kolīdz tas saskaras ar PANAVIA™ Veneer LC Paste. Vieglais, skāriencietējošais praimeris aktivizē tikai adhezīvās virsmas polimerizāciju un rada tūlītēju, noturīgu sasaisti ar emalju un dentīnu, taču neietekmē cementa cietēšanu un tādējādi - arī apstrādes laiku.

 

APSTRĀDES LAIKS
Cementēšanas procedūru laikā apstrādes laiku būtiski ietekmē vairāki ārējie faktori. PANAVIA™ Veneer LC tehnoloģijā šie faktori ir ņemti vērā.
Skāriencietināšanas tehnoloģija ļauj nekavējoties hermetizēt zoba saskarsmes virsmu, kas ir augstās adhēzijas noturības pamatā. Cementa
cietēšanas tehnoloģija nodrošina 200 sekunžu apstrādes laiku apkārtējā gaismā* pirms PVLC zaudē teicamo veidošanas elastību. Šo 200
sekunžu laikā varat ērti novietot un koriģēt (vairākus) venīrus. Gala polimerizācija notiek tad, kad tiek veikta gaismošana ar cietināšanas
lampu.
*Apkārtējā gaisma: aptuveni 8000 lux

 

PANAVIA Veneer LC - VIENDABĪGUMS UN VIZUĀLAIS IZSKATS

JAUNAS PILDVIELAS
PANAVIA™ Veneer LC teicamo apstrādi sekmē nesen izstrādātās lodveida silīcija pildvielas un nanoklāsteru pildvielas (pildvielas noslodze: 66 wt%, 47 vol%). Cementa tiksotropisko īpašību dēļ nenotiek sēšanās vai nobīde. PANAVIA™ Veneer LC nodrošina kontrolētu uzklāšanu, cements paliek uzklāšanas vietā, taču labi plūst venīra(-u) novietošanas laikā.
Cementa viendabīguma un kārtas plānuma (≈ 8 μm) dēļ PANAVIA™ Veneer LC nodrošina plānu, vienmērīgu cementa slāni. Tādējādi tiek sekmēta viegla nosēdināšana bez traucējumiem. Līdztekus tam, tiek lietotas tikai nelielas, lodveida pildvielas (daļiņu izmērs: 0,05 μm – 8 μm), kas nodrošina īpaši estētiskas un gludas piemales, kā arī sekmē pulēšanu un spīduma noturību.

SILĪCIJA PILDVIELAS
Nesen izstrādātās cementa lodveida silīcija pildvielas nodrošina, ka cements paliek uzklāšanas vietā, taču labi plūst venīra nosēdināšanas laikā. Nodrošina vieglu uzlikšanu bez nobīdes vai sēšanās. Veicot uzklāšanu uz restaurācijas, sveķu cements nelīp pie uzklāšanas uzgaļa - šī īpašība tiek panākta, pastai pievienojot nanoklāsteru pildvielas.

 

Jaunie pildvielu veidi rada
teicamu gludumu, spīduma
noturību, kā arī vienkāršu
apstrādi.

VISKOZITĀTE UN TIKSOTROPIJA
Cementa viskozitāte ir būtiska, un tai jābūt pietiekamai zemai, lai novērstu restaurācijas plaisāšanu novietošanas laikā. Vienlaikus cements nedrīkst būt tikt plūstošs, lai tas notecētu uzklāšanas laikā un sēstos apstrādes laikā. Tā kā PANAVIA™ Veneer LC satur optimizētu pildvielas/sveķu maisījumu, tā viskozitāte mainās atkarībā no spiediena. Šo fenomenu dēvē par tiksotropiju. Pasta kļūst plūstošāka zem spiediena venīra novietošanas un koriģēšanas laikā. Spiedienam mazinoties, viskozitāte atjaunojas. PANAVIA™ Veneer LC tiksotropisko īpašību dēļ pastu var viegli izkliedēt un restaurācijas novietošanai ir vajadzīgs neliels spiediens, turklāt lieko materiālu ir viegli noņemt. Īsāk sakot: maksimāla kontrole.

What did you miss this summer?

The vacation period is over and we all are slowly returning back to our everyday routines and work. With all the travel and holidays in the last months you might have missed this great article in the LabLine Summer edition: Graftless solutions and implant-supported monolithic zirconia fixed prostheses.

 

It is an extensive, beautiful and detailed case report created and documented by team of well known and respected KOLs: Fortunato Alfonsi, Antonio Barone, Marco Stoppaccioli, Romeggio Stefano and Vincenzo Marchio.

 

Check it out by clicking here.

 

 

Laminate veneer restoration

LAMINATE VENEER RESTORATION
USING LITHIUM DISILICATE


WITH PANAVIA™ Veneer LC (Clear)
Case by Yohei Sato (DMD, PhD) and Keisuke Ihara (CDT)

Fig. 1 The patient visited would like to have the a aesthetics
of the maxillary right and left lateral incisors improved.

Fig. 2 A silicon guide fabricated from a diagnostic wax model
was applied and the necessary clearances were determined.

Fig. 3 Since the lateral teeth are microdonts, the
preparation of each abutment was completed by simply
exposing a fresh enamel surface to be covered with
laminate veneers.

Fig. 4 A layer of porcelain was applied on the lithium
disilicate substrate, to complete the laminate veneers.

Fig. 5 The veneer was conditioned according to the
prosthesis‘ IFU. After trial fitting, the intaglio surface of the
laminate veneer was cleaned with KATANA™ Cleaner.

Fig. 6 CLEARFIL™ CERAMIC PRIMER PLUS was applied and
dried to prime the restoration.

Fig. 7 The preparation was cleaned with KATANA™ Cleaner.
Applied and rubbed for more than 10 seconds. Then, it
was washed off sufficiently (until the cleaner color had
completely disappeared), and dried with compressed air.

Fig. 8 K-ETCHANT Syringe was applied and left for 10
seconds before water-rinsing and compressed air-drying.

Fig. 9 PANAVIA™ V5 Tooth Primer was applied and left for 20
seconds before mild compressed-air drying.

Fig. 10 PANAVIA™ Veneer LC Paste was applied to the
intaglio surface of the laminate veneer.

Fig. 11 The laminate veneer was seated and the fit
checked. Then, the excess cement was tack-cured (not
more than 1 second at each point) and removed. Finally,
the restoration was light-cured and finished.

FINAL SITUATION

Fig. 12 The laminate veneer restorations one month after
placement. The morphology and color of the right and
left lateral incisors have been improved, providing a good
balance to the entire anterior dentition.

 

 

LAMINATE VENEER RESTORATION
USING KATANA™ Zirconia STML


WITH PANAVIA™ Veneer LC (Clear)
Case by Yohei Sato (DMD, PhD) and Keisuke Ihara (CDT)

 

Fig. 1 The patient was referred by an orthodontist. The main
complaints were improper aesthetics of the teeth due to dark
triangles betwen the teeth and incisal wear.

Fig. 2 On the basis of the pre-treatment diagnosis using
a mockup, the teeth were prepared, with keeping in mind
that the enamel should be preserved to the maximal extent
possible.

Fig. 3 A fixation retainer was present at the palatal side,
making it difficult to take coventional silicon impressions.
Therefore, an intraoral scanner was used.

Fig. 4 A layer of porcelain was applied to each KATANA™
Zirconia STML laminate veneer to complete the restorations.
The inner surface of each restoration was sandblasted, being
careful to prevent chipping.

Fig. 5 After trial fitting, bonding inhibiting substances as
blood and saliva were removed using KATANA™ Cleaner.

Fig. 6 CLEARFIL™ CERAMIC PRIMER PLUS was applied and
dried using compressed air.

Fig. 7 The surface of each tooth was cleaned and treated
with K-ETCHANT Syringe for 10 seconds before washing it
away with water and drying with compressed air.

Fig. 8 PANAVIA™ V5 Tooth Primer was applied and left f

Fig. 9 PANAVIA™ Veneer LC Paste was applied and the
laminate veneers were seated. For this case, we placed six
veneers during one session.

Fig. 10 The unpolymerized excess paste was removed with
a brush according to the wet clean-up technique.

Fig. 11 The result after final light curing. Since the excess
cement was easily removed, there were almost no cement
residues.

FINAL SITUATION

Fig. 12 Result one month after placement of the laminate
veneer restorations. The marginal gingiva has been improved
thanks to the good fit of the laminate veneer restorations.